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N’N’ Dicyclohexyl Carbodiimide (1,3 DCC)

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N,N′-Dicyclohexylcarbodiimide is a widely used reagent in organic chemistry, especially for peptide synthesis, where it facilitates amide bond formation. It is a white crystalline solid and operates via activation of carboxylic acids to form stable intermediates. DCC is also used in esterification and dehydration reactions. Care is required as the byproduct, dicyclohexylurea, can be difficult to remove.

  • Additional Information

    N,N′-Dicyclohexylcarbodiimide (1,3-DCC)


    Product Summary:

    • CAS Number: 538-75-0

    • Molecular Formula: C13H22N2

    • Molecular Weight: 206.33 g/mol

    • Synonyms: DCC

    • Packaging: 25 kg HDPE drum or packets or bags

    • Solubility: Soluble in dichloromethane, DMF

    • Storage: Cool, dry place; avoid moisture

    • Toxicity: Skin sensitizer; use PPE

    Applications:

    • Peptide and amide synthesis

    • Coupling agent for esters

    • Facilitates amide bond formation in pharmaceutical manufacturing
    • Esterification and amidation reactions in organic synthesis
    • Preparation of polymers and dendrimers
    • Precursor for agrochemicals

    • Coupling agent in peptide synthesis


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