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N-Hydroxysuccinimide (NHS) is a white crystalline compound used primarily in peptide coupling chemistry. It activates carboxyl groups for amide bond formation when used in conjunction with carbodiimides like DCC or EDC. NHS esters are also common in bioconjugation and protein labeling. NHS increases the efficiency and specificity of acylation reactions in both lab and industry.
Product Summary:
CAS Number: 6066-82-6
Molecular Formula: C4H5NO3
Molecular Weight: 115.09 g/mol
Synonyms: NHS
Packaging: 25 kg HDPE drum or bags or packets
Solubility: Soluble in water, methanol
Storage: Store in sealed container, dry atmosphere
Toxicity: Low toxicity; avoid prolonged exposure
Applications:
Peptide synthesis
Protein labeling and bioconjugation
Coupling agent for activated esters