N-Hydroxysuccinimide

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N-Hydroxysuccinimide (NHS) is a white crystalline compound used primarily in peptide coupling chemistry. It activates carboxyl groups for amide bond formation when used in conjunction with carbodiimides like DCC or EDC. NHS esters are also common in bioconjugation and protein labeling. NHS increases the efficiency and specificity of acylation reactions in both lab and industry.

  • Additional Information

    N-Hydroxysuccinimide


    Product Summary:

    • CAS Number: 6066-82-6

    • Molecular Formula: C4H5NO3

    • Molecular Weight: 115.09 g/mol

    • Synonyms: NHS

    • Packaging: 25 kg HDPE drum or bags or packets

    • Solubility: Soluble in water, methanol

    • Storage: Store in sealed container, dry atmosphere

    • Toxicity: Low toxicity; avoid prolonged exposure

    Applications:

    • Peptide synthesis

    • Protein labeling and bioconjugation

    • Coupling agent for activated esters

    •  Amide bond formation in peptide synthesis
    • Conjugation of biomolecules in biochemistry
    • Preparation of NHS esters for antibody labeling
    • Precursor in cross-linking agents for polymer chemistry

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