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Ketosulfone is a key pharmaceutical intermediate used in the synthesis of Etoricoxib, a selective COX-2 inhibitor. This compound contains both a ketone and sulfone functional group, allowing for versatile synthetic transformations, especially in cyclization and ring-closing reactions. It is a high-purity intermediate, manufactured under GMP-like conditions to ensure suitability for final drug production. Its use is critical in ensuring the efficacy and safety profile of Etoricoxib.
Description:
Ketosulfone is a key pharmaceutical intermediate used in the synthesis of Etoricoxib, a selective COX-2 inhibitor. This compound contains both a ketone and sulfone functional group, allowing for versatile synthetic transformations, especially in cyclization and ring-closing reactions. It is a high-purity intermediate, manufactured under GMP-like conditions to ensure suitability for final drug production. Its use is critical in ensuring the efficacy and safety profile of Etoricoxib.
Product Summary:
CAS Number: 140104-75-6
Molecular Formula: C10H8O4S
Molecular Weight: 224.23 g/mol
Synonyms: Etoricoxib intermediate
Packaging: 25 kg fiber drum
Solubility: Soluble in DCM, methanol
Storage: Cool, dry place; avoid exposure to moisture
Toxicity: Non-carcinogenic; avoid prolonged exposure
Applications:
Intermediate for Etoricoxib synthesis
Used in COX-2 inhibitor drug research
Building block for heterocyclic compounds
