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Ethyl-4-chloroacetoacetate is a chlorinated derivative of acetoacetic acid ester and serves as an important building block in the synthesis of heterocycles and pharmaceuticals. The compound offers selective reactivity due to the presence of a chloro substituent at the γ-position, facilitating ring-forming reactions and nucleophilic substitutions. It finds wide application in the synthesis of pyrazoles, pyridines, and other biologically active scaffolds.
Description:
Ethyl-4-chloroacetoacetate is a chlorinated derivative of acetoacetic acid ester and serves as an important building block in the synthesis of heterocycles and pharmaceuticals. The compound offers selective reactivity due to the presence of a chloro substituent at the γ-position, facilitating ring-forming reactions and nucleophilic substitutions. It finds wide application in the synthesis of pyrazoles, pyridines, and other biologically active scaffolds.
Product Summary:
CAS Number: 4044-65-9
Molecular Formula: C6H9ClO3
Molecular Weight: 164.59 g/mol
Synonyms: Ethyl 4-chloro-3-oxobutanoate
Packaging: 200 kg HDPE drum
Solubility: Miscible with most organic solvents
Storage: Keep in cool, dry area
Toxicity: Harmful if ingested or inhaled
Applications:
Synthesis of pharmaceuticals and fine chemicals
Intermediate for heterocyclic compounds
Starting material for insecticides and fungicides
