Description:
DFTA, or 2,4-Difluoro-2-(1H-1,2,4-triazol-1-yl)acetophenone, is a key intermediate in the synthesis of the antifungal drug Fluconazole. This compound is crucial in constructing the pharmacophore responsible for Fluconazole's antifungal activity. It possesses a triazole ring and fluorinated aromatic structure, which contribute to its high reactivity and selectivity in targeted synthesis pathways. DFTA is primarily used in API production under controlled environments due to its chemical sensitivity.

Product Summary:

• CAS Number: 86404-63-9

• Molecular Formula: C10H7F2N3O

• Molecular Weight: 223.18 g/mol

• Synonyms: Fluconazole intermediate

• Packaging: 25 kg fiber drum

• Solubility: Soluble in acetone, dichloromethane

• Storage: Store in a dry, cool environment

• Toxicity: Handle with care; may cause irritation

Applications:

• Intermediate in Fluconazole synthesis

• Research in triazole-based antifungals